![]() VXN does not have any alternative mRNA splice variants. The orthologs of vexin all show conservation of the SH3 protein domain family as well as a domain of unknown function (DUF4648). ![]() The N-terminus and C-terminus are highly conserved regions across both distant and close orthologs. The gene has not been found in any plants, fungi or single celled organisms. ![]() The most distant ortholog of VXN is in Callorhinchus milli, which diverged from the human version of the gene an estimated 482.9 million years ago. Vexin is found in all classes of vertebrates, including mammals, birds, fish, reptiles and amphibians. No human paralogs for VXN have been identified Orthologs Phylogentic tree of select orthologs of the gene VXN. Gene neighborhood of VXN along the forward strand of chromosome 8. VXN is flanked by alcohol dehydrogenase iron containing 1 and Myb proto-oncogene like 1. VXN is found along the plus strand of chromosome 8. VXN is found to be highly expressed in regions of the brain and spinal cord.
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